Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Citation: Boominathan, MiRNA-based therapy for Cancer: MiRNA-346 increases the expression of the guardian of the genome p53 via down regulation of its target gene, 20/October/2014, 16.19, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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Significance: This study suggests that miR-346, by decreasing the expression of its target gene, it may increase the expression of p53. Thus, pharmacological formulations encompassing “miR-346 or its activators” may be used to inhibit tumorigenesis and metastasis.
* Research cooperation
