Teacher’s day special
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We wish everyone a happy Teacher’s day. On this special occasion, we are happy to announce that ideas posted today (05/September/2014) will be available to the use of Scientists/Professors/Physicians/Researchers for free.
So, there will be no terms and conditions for the ideas posted today (05/September/2014). Each idea posted will be served first come, first served basis.Write to info@genomediscovery.org for more details about the idea posted.
Dr L Boominathan PhD
CEO & CSO, GBMD.
The 1989 Noble prize winner in Chemistry, Prof. Thomas R. Cech from the University of Colorado BioFrontiers Institute, USA has published a research paper in the 13 December 2012 Nature (492(7428):285-9; I.F: >35) stating that “The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity.” This study provides mechanistic insights into how TPP1 regulates telomerase function.
In connection with this finding, Dr Boominathan, Founder Director-cum-chief scientist of GBMD, reports that: MiRNA-based therapy for Human Cancer: 17α-E2 (an estrogen derivative) suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) via up regulation of its target genes. Remarkably, over 90% human tumors over express telomerase, suggesting that inhibition of its activity may increase the efficacy of anticancer therapy. Together, this study suggests that pharmacological formulations encompassing “17α-E2 or its analogues“ can be used to treat human cancers.
Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Web: http://genomediscovery.org
Citation: Boominathan, L., MiRNA-based therapy for Human Cancer: 17α-E2 (an estrogen derivative) suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) via up regulation of its target genes, 05/September/2014, 7.45 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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