A study from Watson School of Biological Sciences shows that SRSF1 is a critical transcriptional target of c-MYC. This study was published in the Feb 20, 2012 Cell Rep by Prof. Dr Krainer AR & Das, Watson School of Biological Sciences, USA.
On the foundation of this interesting finding, Dr L Boominathan, Director-cum-chief Scientist of GBMD, reports here that: MiRNA-based therapy for human cancers: The reprogramming protein Oct-4 increases the expression of SRSF1 via up regulation of its target gene. This data suggest that Oct-4, by increasing the expression of SRSF1, it will increase the expression of a number of oncogenic mRNAs in cancer cells.
Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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To cite: Boominathan, MiRNA-based therapy for human cancers: The reprogramming protein Oct-4 increases the expression of SRSF1 via up regulation of its target gene, 19/June/2014, 7.55 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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