Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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Citation: Boominathan, MiRNA-based therapy for Melonama: MiRNA-203 increases the expression of ADAR1 and inhibits melanoma progression via down regulation of its target gene, 27/February/2015, 09.10 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
Significance: This study suggests, for the first time, that MiRNA-203, by inducing the expression of its target gene, it may increase the expression of ADAR1. Thereby, it may inhibit melanoma progression. Thus, pharmacological formulations encompassing “MiRNA-203 or its analogues” may be used in the treatment of melanoma.
Amount: $ 500*
Undisclosed information: How MiRNA-203 increases the expression of ADAR1
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