A recent study from the Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts; Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA; and Institute for Biomedical Research, University College London, London, UK shows that “Nociceptive sensory neurons drive interleukin-23-mediated psoriasiform skin inflammation.” This study was published in the Apr 23 2014 Nature by Prof Ulrich H. von Andrian, Lorena Riol-Blanco, and others.
On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: MiRNA-based therapy for Psoriasis: MiRNA-10b inhibits psoriasiform skin inflammation via up regulation of its target gene. This study suggests that MiRNA-10b, by increasing the expression of its target gene, it may alleviate the interleukin-23-mediated psoriasiform skin inflammation. Together, this study suggests that pharmacological formulations encompassing “MiRNA-10b or its activators” may be used to treat psoriasiform skin inflammation.
Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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To cite: Boominathan, L., MiRNA-based therapy for Psoriasis: MiRNA-10b inhibits psoriasiform skin inflammation via up regulation of its target gene, 23/September/2014, 10.28 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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