A recent study from the School of Medicine and Multidisciplinary Cardiovascular Research Centre, University of Leeds, Leeds LS2 9JT, UK shows that “Piezo1 integration of vascular architecture with physiological force.” This study was published in the August 10 2014 Nature by Prof David JB and others.
On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: MiRNAs-based anti-angiogenic and anti-atheroscelorotic therapy: Tumor suppressor p53, p63 and p73 regulate new blood vessel formation via down regulation of Piezo1 or Fam38a. This study suggests that p53/p63/p73, by increasing the expression of its target miRNAs, it may regulate new blood vessel formation in response to mechanical strain. Together, this study suggests that pharmacological formulations encompassing“p53/p63/p73 regulators or its target miRNAs” may be used to treat diseases such as cancer and atheroscelorosis.
Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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To cite: Boominathan, MiRNAs-based anti-angiogenic and anti-atheroscelorotic therapy: Tumor suppressor p53, p63 and p73 regulate new blood vessel formation via down regulation of Piezo1 or Fam38a, 20/August/2014, 12.09 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.orgCourtesy: When you cite drop us a line at info@genomediscovery.org
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