Molecular therapy for body weight control, energy homeostasis and TIIDM: Lactulose (Brand names: Cholac, Generlac, Consulose, Duphalac), a non-absorbable sugar that aids in the treatment of constipation and hepatic encephalopathy,  decreases CADM1 and its downstream target genes that inhibit glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 3/March/2017, 9.10 am