Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Citation: Boominathan, Molecular therapy for cancer: BMP4 suppresses the expression of Notch1 and Notch2 via up regulation of its target gene, 16/October/2014, 7.15 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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Significance: This study suggests that BMP4, by increasing the expression of its target gene, it may suppress the expression of Notch1 and Notch2. Thus, pharmacological formulations encompassing “BMP4 activators“ may be used to inhibit tumorigenesis and metastasis.