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Idea Proposed/Formulated byDr L Boominathan Ph.D.

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CitationBoominathan, Molecular therapy for Cancer: Tumor suppressor MiRNA miR-29c increases the expression of tumor suppressor PTEN via down regulation of its target gene, 29/January/2015, 22.41, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Significance: PTEN is the second most mutated gene in human cancer. This study suggests, for the first time, that miR-29c, by suppressing the expression of its target gene, it may increase the expression of PTEN. Thereby, it may promote tumor suppression. Thus, pharmacological formulations encompassing            ” miR-29c  or its activators”  may be used to inhibit the progression of tumors.

Amount: $ 300

Undisclosed information: How miR-29c increases the expression of tumor suppressor PTEN

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