Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/
Citation: Boominathan, Molecular therapy for Cancer: Tumor suppressor p53 suppresses the expression of 6-phosphofructo-2-kinase/fructose‑2,6-bisphosphatase-3 (PFKFB3) and inhibits proliferation, migration, and invasion of cancer cells via up regulation of its target gene, 14/February/2015, 13.14, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
Significance: This study suggests that p53, by increasing the expression of its target gene, it may decrease the expression of PFKFB3. Thereby, it may inhibit proliferation, migration, and invasion of cancer cells. Thus, pharmacological formulations encompassing “p53 activators” can be used to inhibit the progression of human tumors.
Amount: $ 300
Undisclosed information: How p53 suppresses the expression of PFKFB3
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