Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Web: http://genomediscovery.org
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Significance: This study suggests, for the first time, that Roquin, by down regulation of its target gene, it may increase the expression of metastasis suppressor TIMP3. Thus, pharmacological formulations containing “Roquin activators” can be used in the treatment of human cancers.
To cite: Boominathan, Molecular therapy for Human Cancer: Roquin [RING finger and CCCH-type zinc finger domain-containing protein 1] increases the expression of tumor suppressor TIMP3 (TIMP metallopeptidase inhibitor 3) via down regulation of its target gene, 9/March/2015, 11.54 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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* Research cooperation
Undisclosed information: How Roquin increases the expression of TIMP3
