Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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Significance: This study suggests, for the first time, that Roquin, by down regulation of its target gene, it may increase the expression of tumor suppressor Big-h3. Thus, pharmacological formulations containing “Roquin activators” can be used in the treatment of human cancers.
To cite: Boominathan, Molecular therapy for Human Cancer: Roquin [RING finger and CCCH-type zinc finger domain-containing protein 1] increases the expression of tumor suppresor Big-h3 via down regulation of its target gene, 15/March/2015, 22.43, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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* Research cooperation
Undisclosed information: How Roquin increases the expression of Big-h3