Significance: This study suggests, for the first time, that TAp63, by increasing the expression of its target gene, it may decrease the expression of angiotensin-converting enzyme (ACE). Thereby, it may: (1) decrease blood pressure; and (2) congestive heart failure. Thus, pharmacological formulations encompassing “TAp63 activators“ may be used to treat patients suffering from metabolic diseases, such as high blood pressure and congestive heart failure.
Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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To cite: Boominathan, Molecular therapy for Metabolic diseases: TAp63 decreases blood pressure and inhibits congestive heart failure via down regulation of angiotensin-converting enzyme (ACE) expression, 24/March/2015, 8.58 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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* Research cooperation
Undisclosed information: How TAp63 decreases the expression of angiotensin-converting enzyme (ACE)