Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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Citation: Boominathan, L., Molecular therapy for Myocardial ischemia after myocardial infarction: Argonaute-2 (Ago2) inhibits cardiac ischemia via up regulation of Aldehyde dehydrogenase 2 (ALDH2), 28/March/2015, 23.27, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
Significance: The study presented here suggests that Ago2, by decreasing the expression of its target genes, it may increase the expression of Aldehyde dehydrogenase 2 (ALDH2). Thereby, it may inhibit Myocardial ischemia. Thus, pharmacological formulations encompassing “Ago2 activators” may be used to inhibit myocardial ischemia following myocardial infarction.
Undisclosed information: How Ago2 increases the expression of Aldehyde dehydrogenase 2 (ALDH2)
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