A recent study from the Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts; Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA; and Institute for Biomedical Research, University College London, London, UK shows that “Nociceptive sensory neurons drive interleukin-23-mediated psoriasiform skin inflammation.” This study was published in the Apr 23 2014 Nature by Prof Ulrich H. von Andrian, Lorena Riol-Blanco, and others.
On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Molecular therapy for Psoriasis: Tumor suppressor Menin1 (MEN1) inhibits psoriasiform skin inflammation via up regulation of its target gene. This study suggests that Menin1, by increasing the expression of its target gene, it may alleviate the interleukin-23-mediated psoriasiform skin inflammation. Together, this study suggests that pharmacological formulations encompassing “Menin1(MEN1) or its activators” may be used to treat psoriasiform skin inflammation.
Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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To cite: Boominathan, L., Molecular therapy for Psoriasis: Tumor suppressor Menin1 (MEN1) inhibits psoriasiform skin inflammation via up regulation of its target gene, 1/August/2014, 07.33 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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