Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/
Citation: Boominathan, Natural product-based anticancer therapy: Ursolic acid, enriched in apples, increases the expression of 15-hydroxyprostaglandin dehydrogenase (15-PGDH/HPGD) via down regulation of its target gene, 22/March/2015, 22.58, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
Significance: This study suggests, for the first time, that Ursolic acid, by decreasing the expression of its target gene, it may increase the expression of 15-hydroxyprostaglandin dehydrogenase (15-PGDH/HPGD). Thereby, it may inhibit cancer progression. Thus, pharmacological formulations encompassing “Ursolic acid or its analogues” can be used to inhibit the progression of human tumors.
Undisclosed information: How Ursolic acid increases the expression of 15-hydroxyprostaglandin dehydrogenase (15-PGDH/HPGD)
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