Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/
Citation: Boominathan, Natural product-based antimetastatic therapy: ING1b suppresses the expression Lymphoid enhancer-binding factor-1 (LEF1) via up regulation of its target gene, 19/January/20145, 9.53 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
Significance: This study suggests, for the first time, that ING1b, by increasing the expression of its target gene, it may inhibit the expression of Lymphoid enhancer-binding factor-1 (LEF1). Thereby, it may inhibit the migration and invasion of prostate cancer cells. Thus, pharmacological formulations encompassing “ING1b or its activators” may be used to inhibit the progression of metastatic human tumors.
Amount: $ 300
Undisclosed information: How ING1b suppresses the expression of LEF1.
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* Research cooperation