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Idea Proposed/Formulated byDr L Boominathan Ph.D.

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CitationBoominathan, Natural product-based therapy for cancer: Cirsilol (3′,4′,5-trihydroxy-6,7-dimethoxyflavone), a flavone isolated from Achillea fragrantissima, suppresses the expression of RNA polymerase III via down regulation of its target gene, 22/March/2015, 22.22, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Amount: $ 300

Undisclosed information: How Cirsilol increases the expression of RNA polymerase III

Significance: Cirsilol, by increasing the expression of its target gene, it may suppress the expression of RNA polymerase III. Thereby, it may inhibit tumor progression. Thus, pharmacological formulations encompassing “Luteolin or its analogues” may be used to inhibit cancer progression. 

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