Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Web: http://genomediscovery.org
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To cite: Boominathan, Natural product-based therapy for Cancer: N-arachidonoyl ethanolamine decreases glutathione levels, increases reactive oxygen species levels and inhibits cancer cell proliferation via up regulation of its target gene, 30/October/2014, 10.16 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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Undisclosed information: A mechanistic insight into how N-arachidonoyl ethanolamine decreases glutathione levels, increases reactive oxygen species levels and inhibits cancer cell proliferation.
Significance: The result presented here suggests that N-arachidonoyl ethanolamine, by decreasing the expression of its target gene, it may decrease glutathione levels, increase reactive oxygen species levels and inhibit cancer cell proliferation. Thus, pharmacological formulations encompassing ” N-arachidonoyl ethanolamine or its analogues” can be used to treat cancer.