Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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Citation: Boominathan, Natural product-based therapy for disorders of salt overload and Hypertension: Curcumin, the main component of turmeric, increases the expression of Atrial natriuretic peptide (ANP) and decreases blood pressure via down regulation of its target gene, 07/February/2016, 22.43, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
Significance: This study suggests, for the first time, that Curcumin, by suppressing the expression of its target gene, it may increase the expression of Atrial natriuretic peptide (ANP). Thereby, it may inhibit blood pressure. Thus, pharmacological formulations encompassing “Curcumin or its analogues” may be used to treat disorders of salt overload, including hypertension.
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Undisclosed information: How Curcumin increases the expression of Atrial natriuretic peptide (ANP)