Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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Citation: Boominathan, Natural product-based therapy for increasing Longevity in Females: SMAD7 lowers IGF-1 levels, increases survival and the life expectancy in females, via up regulation of its target gene, 2/September/2014, 6.33 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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Significance: SMAD7, by increasing the expression of its target miRNA, it may: (1) decrease the expression of IGF-1; (2) prolong the survival; (3) and the life expectancy of females. Thus, pharmacological formulations encompassing “SMAD7 activators” may prolong the life expectancy of females.