Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/
Citation: Boominathan, Natural product-based therapy for Metastatic tumors: Sulindac, an anti-inflammatory drug, increases the expression of tumor suppressor CCM1/KRIT1 via down regulation of its target gene, 1/March/2015, 10.07 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
Significance: This study suggests, for the first time, that Sulindac, by suppressing the expression of its target gene, it may increase the expression of CCM1/KRIT1. Thereby, it may inhibit tumor progression. Thus, pharmacological formulations encompassing “Sulindac or its analogues” may be used to inhibit the progression of tumors.
Amount: $ 300
Undisclosed information: How Sulindac increases the expression of CCM1/KRT1
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