Natural product-based therapy for Stress-induced memory loss: Curcumin, the major component of turmeric, promotes memory formation via down regulation of Cortactin and Rac1, 20/August/2014, 11.13 am

Natural product-based therapy for Stress-induced memory loss: Curcumin, the major component of turmeric, promotes memory formation via down regulation of Cortactin and Rac1, 20/August/2014, 11.13 am

Natural product-based therapy for Stress-induced memory loss: Curcumin, the major component of turmeric, promotes memory formation via down regulation of Cortactin and Rac1, 20/August/2014, 11.13 am 150 150 Dr Boomi's Genom-2-Discovery Center

A study from the Department of Metabolism and Aging, The Scripps Research Institute, Florida, USA shows that “MicroRNA-182 regulates amygdala-dependent memory formation.”

This study was published in the January 23, 2013 J Neurosci. by Miller CAGriggs EM and others from the Department of Metabolism and Aging, The Scripps Research Institute, Florida, USA.

On the foundation of this interesting finding, Dr L Boominathan, Director-cum-chief Scientist of GBMDreports here that: Natural product-based therapy for Stress-induced memory loss: Curcumin, the major component of turmeric, promotes memory formation via down regulation of Cortactin and Rac1. This study suggests that Curcumin, by increasing its target gene, it may suppress the expression of synapse-enriched regulators of actin such as, Cortactin and Rac1. Together, this study suggests that pharmacological formulations encompassing “Curcumin or its analogues or its derivatives”   may be used to treat patients suffering from memory loss.

Idea Proposed/Formulated byDr L Boominathan Ph.D.

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CitationBoominathan, Natural product-based therapy for Stress-induced memory loss: Curcumin, the major component of turmeric, promotes memory formation via down regulation of Cortactin and Rac1, 20/August/2014, 11.13 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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Significance: This study suggests, for the first time, that curcumin may alleviate stress-induced memory loss and promote memory formation.