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Idea Proposed/Formulated byDr L Boominathan Ph.D.

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CitationBoominathan, Natural-product based therapy  for Acute Renal injury: α-lipoic acid inhibits renal inflammation by inhibiting inflammasome activation pathway, 13/March/2014, 08.06 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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Significance: This study suggests, for the first time, that α-lipoic acid, by increasing the expression of its target gene, it may inhibit the inflammasome activation pathway. Thereby, it may decrease renal inflammation. Thus, pharmacological formulations encompassing “α-lipoic acid or its analogues” may be used to treat renal inflammatory disease.

Undisclosed information: How α-lipoic acid  inhibits the inflammasome activation pathway

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