Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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Citation: Boominathan, Reciprocal regulation between p53 and Nanog in Cancer development: Stem cell protein Nanog suppresses the expression of tumor suppressor p53 via up regulation of its target gene, 15/September/2014, 05.43 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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Significance: This study suggests, for the first time, that Nanog may suppress the expression of stress-responsive tumor suppressor protein p53. Thus, pharmacological formulations encompassing “Nanog regulator” may be used to treat stress-related disorders and cancer.