Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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Citation: Boominathan, Regenerative therapy for DM: ΔNp63α increases insulin-secreting cell mass and function via up regulation of its target genes, 9/October/2014, 15.24, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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Significance: This study suggests, for the first time, that ΔNp63α, by decreasing the expression of its target gene, it increases insulin-secreting cell mass and function. Thereby, it may increase the insulin sensitivity of cellular tissues. Thus, pharmacological formulations encompassing “ΔNp63α or its activators” can be used to treat DM.