Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/
Citation: Boominathan, L., Small molecule-based Lifespan extension therapy: PDGF-B inhibits senescence and extends life span by down regulating the expression of adenylate cyclase 5 (ADCY5), 2/May/2015, 07.07 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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Significance: This study suggests, for the first time, that PDGF-B may extend the lifespan of an individual by suppressing ADCY5/AC5 expression. Thus, pharmacological formulations encompassing “PDGF-B activators“ may be used to extend the life-span of an individual.
Undisclosed information: How PDGF-B suppresses the expression of adenylate cyclase 5 (ADCY5)