Small molecule-based therapy for Alzheimer’s disease: Rubone decreases Tau expression via up regulation of its target gene, 18/October/2014, 8.41 am

Small molecule-based therapy for Alzheimer’s disease: Rubone decreases Tau expression via up regulation of its target gene, 18/October/2014, 8.41 am

Small molecule-based therapy for Alzheimer’s disease: Rubone decreases Tau expression via up regulation of its target gene, 18/October/2014, 8.41 am 150 150 Dr Boomi's Genom-2-Discovery Center

Idea Proposed/Formulated byDr L Boominathan Ph.D.

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CitationBoominathan, L., Small molecule-based therapy for Alzheimer’s disease: Rubone decreases Tau expression via up regulation of its target gene, 18/October/2014, 8.41 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Significance:  It has been shown that decreasing the expression of Tau protein alleviates the pathogenic symptoms-associated with Alzheimer’s disease. This study suggests, for the first time, that Rubone decreases the expression of Tau protein. Thus, pharmacological formulations encompassing “Rubone or its analogues” can be used to treat patients suffering from Alzheimer’s disease and tauopathies.

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