Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Citation: Boominathan, L., Small molecule-based therapy for Cancer: Reversine increases the expression of Foxl2 via down regulation of its target gene, 22/October/2014, 18.52, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
Significance: This study suggests that Reversine, by decreasing the expression of its target gene, it may increase the expression of Foxl2. Therefore, pharmacological formulations encompassing “Reversine or its analogues“ may be used to treat metastatic cancers.
Amount: $200
Undisclosed information: A detailed mechanistic insight into how Reversine inhibits the progression of metastatic cancers.
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