Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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Citation: Boominathan, L., Small RNAs as Lifespan extenders: NR2F2 extends life span by down regulating the expression of Insulin receptor substrate-2, 4/June/2015, 23.55, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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Significance: This study suggests, for the first time, that NR2F2, by decreasing the expression of its target gene, it may suppress the expression of Insulin receptor substrate-2. Thereby, it may increase the lifespan of an individual. Thus, pharmacological formulations encompassing “NR2F2 activators” may be used to extend the life-span of an individual.
Undisclosed information: How NR2F2 suppresses the expression of Insulin receptor substrate-2