TAp73/63/p53-dependent inhibition of a cell surface protein results in suppression of several epithelial cancers 22/November/2012

TAp73/63/p53-dependent inhibition of a cell surface protein results in suppression of several epithelial cancers 22/November/2012

TAp73/63/p53-dependent inhibition of a cell surface protein results in suppression of several epithelial cancers 22/November/2012 150 150

Idea Proposed byDr L Boominathan Ph.D.

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To citeBoominathan, TAp73/63/p53-dependent inhibition of a cell surface protein results in suppression of several epithelial cancers, 22/November/2013, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Description: A cell surface protein that is over expressed in sever epithelial cancers appears to increase the stem cell renewal/proliferation.  We propose here that the expression of this protein is inhibited by TAp73/p63/p53.  This results in inhibition of  proliferation of epithelial cancer cells.