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This year’s Nobel prize winner for Physiology or Medicine Prof. Schekman Randy (from Univ of California, Berkeley, USA) has highlighted the importance of the COPII component Sec23 in vessicle traficking and normal craniofacial development.  

In connection with this finding, Dr Boominathan, Founder Director-cum-chief scientist of GBMD, reports that the tumor suppressor p53/p63/p73 regulates Sec23 expression through its target gene. This finding suggests that the expression of p63/p73/p53 may regulate vessicle traficking and normal craniofacial development through Sec23 Furthermore, p53/p63/p73-regulated Sec23a may control the secretion of metastasis-suppressive proteins. 

Idea Proposed byDr L Boominathan Ph.D.

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To citeBoominathan, The Follow-up of  Nobel’s(Schekman Randy) favorite work: The tumor suppressor p63/p73/p53 regulates Sec23 expression through its target gene, 8/October/2013, 7.40 am,  Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

* Research cooperation

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