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Idea Proposed/Formulated byDr L Boominathan Ph.D.

Web: http://genomediscovery.org

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To citeBoominathan, Therapeutic insight into increasing the functional β-cell mass in DM:  CDX2 increases human pancreatic β-cell proliferation via up regulation of cell cycle protein Cyclin C, 5/April/2015, 12.36 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Significance: CDX2, by decreasing the expression of its target gene, it may increase the expression of  cell cycle protein Cyclin C. Thereby, it may increase human pancreatic β-cell proliferation. Thus, pharmacological formulations encompassing “CDX2 activators” may be used to increase functional β-cell mass in DM.

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Undisclosed information: How CDX2 increases the expression of Cyclin C


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