Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Citation: Boominathan, Therapeutic insight into the treatment tof Age-related Cataract: CDX2 promotes the surivival of lens epithelial cells via up regulation of its target gene, 27/October/2014, 8.48 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
Significance: This study suggests that CDX2, by increasing the expression of its target gene, it may decrease the expression of a number of tumor suppressor proteins. Thereby, it may increase the survival of lens epithelial cells and prevent age-related cataract. Therefore, pharmacological formulations encompassing “CDX2 activators“ may be used to treat Cataract.
Undisclosed information: How CDX2 promotes the survival of lens epithelial cells.
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