A study from University of California, San Diego, and Sanford-Burnham Medical Research Institute, La Jolla, California, USA shows that Inhibition of miR-25 improves cardiac contractility in the failing heart. This study was published in the April 24, 2014 Nature by Prof. Dr Mark Mercola and others from the Department of Bioengineering, University of California, San Diego, and the Muscle Development and Regeneration Program, Sanford-Burnham Medical Research Institute, La Jolla, California, USA.
On the foundation of this interesting finding, Dr L Boominathan, Director-cum-chief Scientist of GBMD, reports here that: Therapeutic insights into restoring the contractility of heart muscle function: Treatment with the Smoothened inhibitor Saridegib (and its analogs) improves cardiac contractility and function via down regulation of its target gene.
Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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To cite: Boominathan, Therapeutic insights into restoring the contractility of heart muscle function: Treatment with the Smoothened inhibitor Saridegib (and its analogs) improves cardiac contractility and function via down regulation of its target gene, 28/April/2014, 6.50 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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