Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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Citation: Boominathan, Therapeutic Insights into Stress-induced impairment of Cognition and Memory: Stress responsive protein p53 suppresses the expression of GlcNAc N-deacetylase/N-sulfotransferase-1 via up regulation of its target gene, 29/August/2014, 09.45 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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Significance: This study suggests that stress induced p53, by decreasing the levels of GlcNAc N-deacetylase/N-sulfotransferase-1, it may promote intellectual impairment and memory deficits. Thus, pharmacological formulations encompassing “p53 inhibitor”may be used to treat stress-induced disorders, involving intellectual and memory impairment.
