Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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Citation: Boominathan, Therapeutic insights into the treatment of amyotrophic lateral sclerosis: Cilostazol alleviates amyotrophic lateral sclerosis via up regulation of HSF1/HSP70i chaperone, 01/October/2014, 06.49 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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Significance: This study suggests that Cilostazol, by increasing the expression of its target gene, it may increase the expression of HSF1/HSP70i chaperone. Thereby, it may inhibit the development of amyotrophic lateral sclerosis. Thus, this study suggests that pharmacological formulations encompassing “Cilostazol or its analogues” may be used to inhibit the disease pathology of amyotrophic lateral sclerosis.