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Idea Proposed/Formulated byDr L Boominathan Ph.D.

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CitationBoominathan, Therapeutic insights into the treatment of hippocampal neurodegeneration and memory loss: Stress-induced gene product MiRNA-29 promotes apoptosis of hippocampal neurons and memory loss via down regulation of its target gene, 14/September/2014, 17.36, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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Significance: This study suggests, for the first time, that prolonged induction of stress-induced MiRNA-29 promotes hippocampal neurodegeneration and memory loss.  Thus, pharmacological formulations encompassing “MiRNA-29 inhibitor or small molecule compounds or miRNAs or SiRNAs that decrease the expression of MiRNA-29 may be used to treat neurodegenerative disorders, including amnesia.

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