Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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Citation: Boominathan, Therapeutic insights into the treatment of Sickle cell disease and β-thalassemias : C-Myc decreases sickling of erythrocytes via up regulation of fetal HbF, 21/September/2014, 09.35 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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Significance: This study suggests that c-Myc, by up regulating the expression of its target gene, it may up regulate the levels of HbF. Thus, pharmacological formulations encompassing “c-Myc activator” may be used to treat: (1) Sickle cell disease ; and (2) β-thalassemias.
* Research cooperation