Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/
Citation: Boominathan, Therapeutic insights into the treatment of Sickle cell disease and β-thalassemias: Ras Responsive Element Binding Protein 1 (RREB) decreases sickling of erythrocytes via up regulation of fetal HbF, 25/September/2014, 06.41 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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Significance: This study suggests that RREB, by regulating the expression of its target gene, it may increase the levels of HbF. Thus, pharmacological formulations encompassing “RREB activator” may be used to treat: (1) Sickle cell disease ; (2) β-thalassemias; and (3) disease conditions that has lower levels of HbF.
* Research cooperation