Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Citation: Boominathan, Treating cancer with an NIDDM drug: Acarbose, the widely used drug in the treatment of T2D, suppresses the expression of Notch1 and Notch2 via up regulation of its target gene, 23/October/2014, 14.36, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/
Significance: This study suggests that acarbose, by increasing the expression of its target gene, it may suppress the expression of Notch1 and Notch2. Thus, pharmacological formulations encompassing “acarbose or its analogues“ may be used to inhibit tumorigenesis and metastasis.
Amount: $300
Undisclosed information: A detailed mechanistic insight into how acarbose suppresses the expression of Notch-1 and Notch-2.
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