Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Web: http://genomediscovery.org
Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/
To cite: Boominathan, Vitamin-based therapy for metastastic hepatocellular carcinoma: 1,25-dihydroxyvitamin D suppresses the expression of ICMT-Rac1 via up regulation of its target gene, 4/November/2014, 13.41, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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* Research cooperation
Amount: $ 300*
Undisclosed information: A mechanistic insight into how 1,25-dihydroxyvitamin D decreases the expression of ICMT-Rac1.
Significance: The result presented here suggests that 1,25-dihydroxyvitamin D, by decreasing the expression of its target gene, it may decrease the expression of ICMT(isoprenylcysteine carboxyl methyltransferase)-Rac1. Thus, Physicians/Clinicians/Health care practitioners may consider treating their cancer patients with 1,25-dihydroxyvitamin D.
