Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Citation: Boominathan, Antiviral therapy: p53 decreases Hepatitis C virus (HCV) entry via down regulation of the receptor for entry into hepatocytes Occludin, 12/October/2014, 10.56 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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Significance: This study suggests, for the first time, that tumor suppressor p53, by decreasing the expression of Occludin, it may decrease the entry of Hepatitis C virus into hepatocytes. Thus, pharmacological formulations encompassing “p53 activators” may be used to prevent the entry of Hepatitis C virus.