Bio-Med Ideas

May 22, 2017

Music-based PD-1 pathway blockade for Human cancer therapy: Music therapy decreases the activity of Glycogen synthase kinase-3β, increases transcription factor T-bet expression, decreases the abundance of co-inhibitory receptor PD-1 on the cell surface of Cytotoxic-T-cells, increases cytotoxic T lymphocyte function and augments anti-tumor activity, via up-regulation of its target gene, 22/May/2017, 11.57 pm

Introduction:What they say:  A recent study from Cell Signalling Section, Division of Immunology, Department of Pathology, Tennis Court Road, University of Cambridge, Cambridge CB2 1QP, UK […]
May 22, 2017

Amino-acid based therapy for Glaucoma: L-Leucine, the branched chain amino acid, increases Nmnat1 expression, increases NAD+ levels, improves neuronal dysfunction, and protects against glaucoma via down regulation of its target gene, 22/May/2017, 11. 55 pm

Introduction: What they say A study from the The Jackson Laboratory, Bar Harbor, ME 04609, USA; Department of Ophthalmology, Tufts University of Medicine, Boston, MA 02111, […]
May 22, 2017

Laminar shear stress-based therapy for pulmonary fibrosis: Laminar shear stress decreases miR-34 expression, increases Sirtuin-1 expression, suppresses tumor suppressor p53 acetylation, prevents apoptosis in Alveolar epithelial cell (AEC), and improves pulmonary fibrosis via up regulation of its target gene, 22/May/2017, 11.54 pm

What we say:  Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Laminar shear stress-based therapy for pulmonary fibrosis: Laminar shear stress decreases miR-34 expression, increases Sirtuin-1 expression, […]
May 22, 2017

Amino-acid based therapy for Inflammatory bowel disease: Leucine, the branched chain amino acid, decreases the expression of oncostatin M, attenuates activation of oncostatin M- oncostatin M receptor pathway in inflamed colon tissues, inhibits inflammatory gene expression, attenuates colonic pathogenesis, and inhibits the progression of inflammatory bowel disease and colitis via down regulation of its target gene, 22/May/2017, 11.50 pm

Introduction: What they say: A study from the Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK Translational Gastroenterology Unit, Nuffield Department of Medicine, University of […]
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