Check our Recent Posts
Total no of Ideas: 10913
Molecular therapy for blood sugar disease: MANF (Mesencephalic astrocyte-derived neurotrophic factor) increases GLP1R and Caveolin-1 (CAV-1) expression, promotes glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM, via up-regulation of its target gene, 17/November/2018, 8.49am
Probiotic-based therapy for diabetic retinopathy: Probiotic Bifidobacterium lactis HY8101 inhibits Soluble epoxide hydrolase (sEH) expression, decreases toxic 19,20-dihydroxydocosapentaenoic acid levels, inhibits pericyte loss, vascular permeability, and inflammation of the eye and progression of diabetic retinopathy, via down-regulation of its target gene, 17/November/2018, 8.35 am
Curry’s main ingredient/ coloring agent Curcumin may extend the lifespan of humans: Curcumin-based Lifespan extension therapy: Curcumin, found in turmeric, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian lifespan by regulating the expression of its target genes, 17/November/2018, 8.16 am
Valproic acid-based therapy for blood sugar disease: Valproic acid increases GLP1R and Caveolin-1 (CAV-1) expression, promotes glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM, via up-regulation of its target gene, 16/October/2018, 11.57 pm
Lighting your way to lower cholesterol, and triglycerides levels: Intense blue light exposure decreases the levels of HMGCR, triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD), via up-regulation of its target gene, 16/November/2018, 11.48 pm
Lengthening the lifespan of mighty humans with a tiny Probiotic Lactobacillus reuteri GMNL-263: Probiotic Lactobacillus reuteri GMNL-263 may increase insulin sensitivity, slow down cardiac aging, and increase lifespan, via up-regulation of BubR1 and others longevity-promoting genes, 16/November/2018, 11.34 pm
Probiotic-based therapy for Squamous cell carcinoma of head and neck (HNSCC): Probiotic Lactobacillus Rhamnosus inhibits BMI1 and AP-1 expression, overcomes chemotherapeutic resistance, promotes chemosensitivity, suppresses cancer stem cells in HNSCC, and inhibits lymph node metastasis, via down-regulation of its target genes, 16/November/2018, 12.03 am
Molecular therapy for Myocardial Infarction: Empagliflozin (trade name Jardiance), used in the treatment of TIIDM, inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction, via up-regulation of PNUTS, 15/November/2018, 11.48 pm
Probiotic-based therapy for prostate cancer bone metastasis: Probiotic Lactobacillus Rhamnosus inhibits the expression of Monoamine oxidase A (MAOA), inhibits Shh-IL6-RANKL signaling network, suppresses tumor-stromal interactions, reduces prostate cancer metastasis and prolongs survival via up regulation of its target gene, 15/November/2017, 11.32 pm
Molecular therapy for cardiac dysfunction: Empagliflozin (trade name: Jardiance), used in the treatment of TIIDM, decreases Mir-29 expression, activates Wnt- signaling and its components GSK3B, ICAT/CTNNBIP1, HBP1, and GLIS2, attenuates pathologic hypertrophy, inhibits fibrosis of the heart tissue, and improves cardiac function, via upregulation of its target gene, 15/November/2018, 11.22 pm
Who we are and what we do
Ideas can even be life changing.
We generate bio-medical/pharma/therapeutic/clinical ideas for the scientific community. Good Ideas are uncommon and unique. This is because everyone’s educational background is different. As a result, every one’s thinking process is different. Consequently, his/her ability to connect/understand complex biological/pathological mechanism differs.