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Total no of Ideas: 10605
Repurposing tuberculosis vaccine into a diabetic vaccine: TB/BCG vaccine, a tuberculosis vaccine, decreases DNA-PPK expression, suppresses phosphorylation of HSP90a, increases AMPK activity, augments mitochondrial biogenesis and energy metabolism, promotes weight loss and exercise endurance and alleviates TIIDM via down-regulation of its target gene, 23/July/2018, 11.14 am
Flu vaccine-based therapy for TIIDM and obesity-associated metabolic deficits: Influenza A (H1N1)/Flu vaccine increases Lipocalin 2 (LCN2) expression, activates an MC4R-dependent anorexigenic pathway, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM via down-regulation of its target gene, 23/July/2018, 11.01 am
Polysaccharide-based anti-infective Therapy: Astragalus polysaccharide, isolated from astragalus membraneous, inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1, respiratory syncytial, Sindbis, and SFV viruses by increasing the Levels of the antiviral Proteins IFITM3, & Interferon-stimulated gene 15, 22/July/2018, 5.41 pm
Reproductive hormone aids in control of body weight, energy homeostasis and TIIDM: FSH(Follicle stimulating hormone), a polypeptide glycoprotein, decreases CADM1 and its downstream target genes that inhibit glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM, via up-regulation of its target gene, 22/July/2017, 5.31 pm
Molecular therapy for aging-associated diseases and Lifespan extension: Enoxacin, a broad-spectrum antibacterial agent, increases NMN/NAD levels, decreases interaction of DBC1 with PARP1, increases PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer and aging via down-regulation of its target gene, 20/July/2018, 11.27 pm
Antiviral therapy for Neuroinvasive West Nile virus: β-(1,3)-glucan/Lentinan(LNT), isolated from mushroom Lentinus edodes, increases the expression of RIPK3, promotes chemokines production, inhibits neuroinflammation, and restricts neuroinvasive West Nile virus production and pathogenesis in neurons via upregulation of its target gene, 20/July/2018, 1.51 pm
Flu vaccine for normalizing blood sugar levels: Influenza A/Flu (H1N1) vaccine-based therapy for blood sugar disease: Influenza A/Flu (H1N1) vaccine increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state, via up-regulation of its target gene Lin28, 20/July/2018, 9.39 am
Flu vaccine preserves your eyes against glaucoma: Influenza A/Flu (H1N1) vaccine-based therapy for glaucoma: Influenza A/Flu (H1N1) vaccine increases Nmnat1 expression, increases NAD+ levels, improves neuronal dysfunction, and protects against glaucoma, via down-regulation of its target gene, 20/July/2018, 9.05 am
Flavonoid your way to decrease blood pressure/sugar and extend lifespan: Quercetin-based Lifespan and healthspan extension therapy: Quercetin, a flavonoid isolated from elder berries and onions, decreases blood sugar and blood pressure levels and prolongs mammalian life span, via down regulation of angiotensin II type I receptor (AT1R), 18/July/2018, 7.47 am
Heat-shock inhibitors (HSPs) as longevity-promoters: HSP-90 inhibitor-based combinatorial therapy for Lifespan extension: A therapeutic mix encompassing 17-DMAG(HSP-90 inhibitor), Ursolic acid, Catalpol, Isoliquiritigenin, Maresin, DIM, Lutein, Maresin, Cholecalciferol (17-DMAGUCIMDLMC) activates autophagy, promotes leanness, increases insulin sensitivity, improves motor function, alleviates ageing feature and extends lifespan, via up regulation of its target gene ATG5 (Autophagy related 5), 18/July/2018, 7.34 am
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Ideas can even be life changing.
We generate bio-medical/pharma/therapeutic/clinical ideas for the scientific community. Good Ideas are uncommon and unique. This is because everyone’s educational background is different. As a result, every one’s thinking process is different. Consequently, his/her ability to connect/understand complex biological/pathological mechanism differs.