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Total no of Ideas: 10488
A salty way to keep the cardiac diseases at bay-hard to believe though(!): Hypertonic saline-based Regenerative therapy for regaining the lost cardiomyocytes in Myocardial patients: Hypertonic saline (10%) increases the expression of ERBB2/Her2 and promotes dedifferentiation of cardiomyocytes via down regulation of its target gene, 23/May/2018, 12.58 am
A fibrous way to strengthen your heart and extend lifespan: β-glucan-based therapy for cardiomyopathy: β-glucan, found abundantly in oats and barley, may suppress tumor suppressor INK4a/p16 expression, inhibit dilated cardiomyopathy and extend life span, via up regulation of its target gene, 23/May/2018, 12.37 pm
A handful of fiber-rich Oats and barley a day keeps the cardiac diseases at bay: Fiber-based Regenerative therapy for regaining the lost cardiomyocytes in Myocardial patients: β-glucan, found abundantly in Oats and barely, increases the expression of ERBB2/Her2 and promotes dedifferentiation of cardiomyocytes via down regulation of its target gene, 23/May/2018, 12.10 am
A salty way to say no to pain: Hypertonic saline-based Pain therapy: Hypertonic saline (10%) increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 22/May/2018, 11.48 pm
A sweet way to say no to myocardial diseases: Sugar-based therapy for cardiac repair and myocardial infarction: Raffinose, a trisaccharide isolated from cotton seed flour, increases Agrin expression, activates Yap and ERK-mediated signaling, replaces scar tissue with functional cardiomyocytes, and promotes cardiomyocyte regeneration and repair after myocardial infarction, via up regulation of its target gene, 22/May/2018, 11.35 pm
A salty way to say no to cardiac diseases-hard to believe though (!): Hypertonic saline-based therapy for attenuating pathogenesis-associated with Myocardial infarction: Hypertonic saline (10%) decreases IRF3 (Interferon regulatory transcription factor-3), GM-CSF (Granulocyte-macrophage colony-stimulating factor) and GRK2(G protein-coupled receptor kinase) expression, inhibits undue leucocyte activation and invasion, suppresses recruitment of inflammatory cells, inhibits ventricular dilation, and promotes heart repair and survival, via up regulation of its target gene, 22/May/2018, 3.45 pm
Awakening the sleeping/cancer-protecting angels in mutant p53-expressing human tumors: Hydrogen-rich saline increases the expression of tumor suppressors genes, such as p53, TA-p73 and TA-p63, TIMP3, and CCM3/KRIT1, and others, induces regression of p53-mutated human tumors, via down regulation of its target gene, 20/May/2017, 4.56 pm
Molecular therapy for Deafness: A therapeutic mix encompassing Lactulose, Cholecalciferol, Ajoene and DIM (LCAD) increases the expression of ATG5 (Autophagy-related 5), prevents aggregation of proteins in inclusion bodies, inhibits hair cell degeneration, improves hearing loss via up regulation of its target genes, 20/May/2018, 4.43 pm
Molecular therapy for cardiomyocyte proliferation and heart regeneration: A pharmaceutical mixture encompassing 3,3′-Diindolylmethane (DIM) Sodium nitrite(NaNO2), and Sodium Sulfide (DIMSNSS) decreases tumor suppressor MiR-128 and cyclin-dependent kinase inhibitor p27 expression, increases SUZ12 expression, increases Cyclin E and CDK2 expression, promotes proliferation/re-entry of postnatal/adult cardiomyocytes, attenuates fibrosis, ameliorates cardiac dysfunction, and promotes heart repair in response to myocardial infarction, via up regulation of its target gene, 20/May/2018, 4.29 pm
A sweet way to strengthen your heart-too good to be true(!): Oligofructose-based therapy for Cardiomyopathy: Agavins (Oligofructose), a new natural sugar isolated from agavi, may suppress tumor suppressor INK4a/p16 expression, and inhibit dilated cardiomyopathy, via up regulation of its target gene, 20/May/2018, 3.36 pm
A glycolipid-based therapy for glucose homeostasis and TIIDM: α-Galactosylceramide (α-gal-cer), a synthetic glycolipid, increases Pax6 and insulin expression, decreases the levels of glucagon, ghrelin and Somatostatin, reduces metabolic stress, improves insulin sensitivity, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 18/May/2018, 2.03 pm
Who we are and what we do
Ideas can even be life changing.
We generate bio-medical/pharma/therapeutic/clinical ideas for the scientific community. Good Ideas are uncommon and unique. This is because everyone’s educational background is different. As a result, every one’s thinking process is different. Consequently, his/her ability to connect/understand complex biological/pathological mechanism differs.