Ageing

September 20, 2019

Senolytics therapy for cardiac repair, cardiac regeneration and cardioprotection: Combinatorial therapy for postnatal Cardiomyocyte proliferation, repair and regeneration:  A two-component Pill consisting of Dasatinib and Quercetin (Pill-DQ) decreases tumor suppressor MiR-128 and cyclin-dependent kinase inhibitor p27 expression, increases SUZ12 expression, increases Cyclin E and CDK2 expression, promotes proliferation/re-entry of postnatal/adult cardiomyocytes, attenuates fibrosis, ameliorates cardiac dysfunction, and promotes heart repair in response to myocardial infarction, via up-regulation of its target gene, 20/September/2019, 7.39 am

Introduction: What they say: A recent study from Department of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, 45267, USA; Key Laboratory […]
September 2, 2019

Eating ample amounts of tomatoes will extend your lifespan: Tomato powder-derived compounds function as longevity promoters: Lycopene and Apo-10-lycopenoic acid, derived from tomato powder, may  increase insulin sensitivity, slow down cardiac aging, and increase lifespan, via up-regulation of BubR1 and others genes, 3/September/2019, 12.25 am

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston, USA; […]
August 28, 2019

Why cigarette smoking is not good for your heart: Mechanistic  and functional insights into how cigarette smoking accelerates cardiac dysfunction: Cigarette smoking augments DNA damage responses, attenuates telomerase expression, promotes telomere shortening, and attenuates cardiomyocyte survival after myocardial infarction, via down regulation of PNUTS and others, 28/August/2019, 1.55 pm

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published, in the 7 March  2013 issue of of […]
August 26, 2019

Consumption of olive oil can lengthen lifespan: Oleic acid-based anti-ageing and Lifespan extension therapy:  Oleic acid, the main constituent of olive oil, increases CHIP levels, increases monoubiquitylation of insulin receptor (INSR), decreases INSR protein levels and enhances lifespan, via down regulation of its target gene, 26/August/2019, 3.07 pm

Introduction: What they say  A study from Institute for Cell Biology, University of Bonn, Ulrich-Haberland Str.  Bonn, Germany; and Institute for Genetics and CECAD Research Center, […]