Ageing

January 12, 2019

Ribonucleic acid-based therapy for aging-associated diseases and Lifespan extension: LncRNA Zeb2-AS1 increases NMN/NAD levels, decreases interaction of DBC1 with PARP1, increases PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer and aging via down-regulation of its target gene, 12/January/2019, 6.39 am

Introduction: What they say A study from Department of Genetics, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA; and […]
January 4, 2019

RNA-based therapy for aging-associated diseases and Lifespan extension: LncRNA BRM inhibits the interaction of DBC1 with PARP1, increases the PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer and aging, via down-regulation of its target gene, 4/January/2019, 10.03 am

Introduction: What they say A study from Department of Genetics, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA; and […]
January 1, 2019

Molecular therapy for aging-associated diseases and Lifespan extension: LncRNA TUG1 decreases the interaction of DBC1 with PARP1, increases the PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer and aging, via down-regulation of its target gene, 1/January/2019, 6.01 am

Introduction: What they say A study from Department of Genetics, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA; and […]
December 31, 2018

Molecular therapy for aging-associated diseases and Lifespan extension: Nicotinamide riboside, a pyridine-nucleoside form of vitamin B3 and precursor to NAD+, increases NMN/NAD levels, decreases interaction of DBC1 with PARP1, increases PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer and aging, via down-regulation of its target gene, 31/December/2018, 6.55 pm

Introduction: What they say A study from Department of Genetics, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA; and […]