Antiviral diseases

October 14, 2017

Antiviral therapy for HIV virus: Nimesulide, a drug used to relieve pain,  increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 15/October/2017, 1.14 am

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that:  Antiviral therapy for HIV virus: Nimesulide, a drug used to relieve pain,  increases Heme […]
October 14, 2017

Antiviral therapy for Neuroinvasive West Nile virus: Rifampicin, an antibiotic used in the treatment of tuberculosis, leprosy, and Legionnaire’s disease, increases the expression of RIPK3, promotes chemokines production, inhibits neuroinflammation, and restricts neuroinvasive West Nile virus production and pathogenesis in neurons via up regulation of its target gene, 15/October/2017, 1.06 am

Introduction: What they say A study from the Department of Immunology, University of Washington, Seattle, WA 98109, USA; Center for Innate Immunity and Immune Disease, University of […]
October 14, 2017

Antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: P-MAPA (Protein Aggregate Magnesium-Ammonium Phospholinoleate-Palmitoleate Anhydride), an immunomodulator,  increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via up regulation of its target gene, 15/October/2017, 12.56 am

Introduction: What they say A study from the Viral Populations and Pathogenesis Unit, Institut Pasteur, CNRS UMR 3569, 25–28 rue du Dr. Roux, 75724 Paris Cedex […]
October 14, 2017

Antiviral therapy against Hepatitis-B virus: Gatifloxacin, an antibiotic drug,  increases the expression of Setd2, methylates STAT1, activates STAT1, promotes trimethylation of IFN-stimulated gene-15, and restricts Hepatitis-B virus (HBV) production and pathogenesis via up regulation of its target gene, 15/October/2017,  12.38 am

Introduction: What they say A study from the Institute of Immunology, Zhejiang University School of Medicine, Hangzhou 310058, China; and Institute of Immunology, Zhejiang University School […]