Antiviral diseases

February 28, 2019

Probiotics function as anti-HIV agents: Probiotic Bacillus subtilis B10 increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production, via upregulation of its target gene, 28/February/2019, 8.09 am

National Science day special ********* We wish everyone a very happy national science day. On this special occasion, we are happy to announce that Bio-Med/Pharma/Therapeutic/Clinical ideas posted […]
January 29, 2019

Natural product-based therapy for attenuating pathogenesis-associated with Myocardial infarction: Rutin decreases IRF3, GM-CSF (Granulocyte-macrophage colony-stimulating factor) and GRK2(G protein-coupled receptor kinase) expression, inhibits undue leucocyte activation and invasion, suppresses recruitment of inflammatory cells, inhibits ventricular dilation, and promotes heart repair and survival via upregulation of its target gene, 29/January/2018, 7.36 am

Introduction: What they say: A recent study from Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, USA; and Cardiovascular Research Center, Massachusetts General Hospital and […]
January 29, 2019

Repurposing the anti-psychotic drug Thioridazine into an anti-infective agent:  Thioridazine (Trade name: Mellaril) inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the antiviral Proteins IFITM3, & Interferon-stimulated gene 29/January/2019, 6.20 am

Introduction: What they say: A study from the Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard Medical School, Charlestown, MA 02129, USA […]
December 1, 2018

Probiotics function as anti-HIV agents: Probiotic Lactobacillus casei strain shirota (LcS) increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production, via upregulation of its target gene, 2/December/2018, 12.15 am

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Probiotics function as anti-HIV agents: Probiotic Lactobacillus casei strain shirota (LcS) increases Heme oxygenase 2 […]