Antiviral therapeutics

March 26, 2019

Repurposing the anti-bacterial agent Ciprofloxacin as an antiviral agent: Ciprofloxacin-based antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: Ciprofloxacin (brand name: Ciloxan, Cipro, Neofloxin) increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication, via upregulation of its target gene, 26/March/2019, 11.23 pm

Introduction: What they say A study from the Viral Populations and Pathogenesis Unit, Institut Pasteur, CNRS UMR 3569, 25–28 rue du Dr. Roux, 75724 Paris Cedex […]
March 26, 2019

Repurposing the antibiotic Enoxacin into a broad-spectrum anti-infective agent: Enoxacin (Trade names: Comprecin, Enoksetin, Enoxen, Enroxil, Enoxin, Enoxor, Flumark and others),  a fluoroquinolone-based antibiotic commonly used in the treatment of urinary tract infections and gonorrhea,  inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, & Interferon-stimulated gene 15, 26/March/2019, 10.38 pm

Introduction: What they say: A study from the Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard Medical School, Charlestown, MA 02129, USA […]
March 25, 2019

Repurposing the antibiotic Ciprofloxacin into a broad-spectrum anti-infective agent: Ciprofloxacin, a drug used to treat bacterial infections,  inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, & Interferon-stimulated gene 15, 25/March/2019, 8.42 am

Introduction: What they say: A study from the Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard Medical School, Charlestown, MA 02129, USA […]
March 23, 2019

Interleukin-based Anti-infective Therapy: IL-24  inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, & Interferon-stimulated gene 15, 23/March/2019, 7.04 pm

Introduction: What they say: A study from the Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard Medical School, Charlestown, MA 02129, USA […]