Antiviral therapeutics

September 28, 2017

Natural product-derived antiviral therapy for HIV virus: Nordihydroguaiaretic acid (NDGA), isolated from creosote, increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 29/September/2017, 12.40 am

Introduction: What they say A study from the Department of Biochemistry and Molecular Biophysics and Department of Microbiology and Immunology, Howard Hughes Medical Institute, Columbia University, […]
September 26, 2017

Natural product-derived antiviral therapy against Neuroinvasive West Nile virus: Nordihydroguaiaretic Acid (NDGA), isolated from Creosote, increases the expression of RIPK3, promotes chemokines production, inhibits neuroinflammation, and restricts neuroinvasive West Nile virus production and pathogenesis in neurons via up regulation of its target gene, 26/September/2017, 6.41 am

Introduction: What they say A study from the Department of Immunology, University of Washington, Seattle, WA 98109, USA; Center for Innate Immunity and Immune Disease, University of […]
September 26, 2017

Antiviral therapy against Hepatitis-B virus: Lamivudine, an anti-HIV drug, increases the expression of Setd2, methylates STAT1, activates STAT1, promotes trimethylation of IFN-stimulated gene-15, and restricts Hepatitis-B virus (HBV) production and pathogenesis via up regulation of its target gene, 26/September/2017,  6.33 am

Introduction: What they say A study from the Institute of Immunology, Zhejiang University School of Medicine, Hangzhou 310058, China; and Institute of Immunology, Zhejiang University School […]
September 24, 2017

Antiviral therapy for HIV virus: Combvir [Zidovudine (ZDV)/Azidothymidine (AZT) and Lamivudine], an anti-HIV drug, increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 24/September/2017, 11.59 am

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that:  Antiviral therapy for HIV virus: Combvir [Zidovudine (ZDV)/Azidothymidine (AZT) and Lamivudine], an anti-HIV drug, increases Heme oxygenase […]