Cancer metastasis

A sweet way to treat Metastatic cancers: Xylobiose, a disaccharide of xylose, increases the expression of tumor/metastatic suppressors KIBRA and GAS5, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up-regulation of its target gene, 14/November/2018, 11.58 pm
A sweet way to treat Metastatic cancers: Xylobiose, a disaccharide of xylose, increases the expression of tumor/metastatic suppressors KIBRA and GAS5, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up-regulation of its target gene, 14/November/2018, 11.58 pm 960 720 Dr Boomi's Genom-2-Discovery Center

From Significance of the study to Public health relevance:  Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more than half of them…

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Probiotic-based therapy for metastatic prostate cancer: Lactobacillus Rhamnosus inhibits the expression of CDC42, CDC42EP3, RAC1 and ARPC5, and GAS6, suppresses the expression of stem cell molecules CD44 and EZH2, promotes epithelial phenotype, suppresses tumorigenesis, migration, invasion, stem cell regeneration and metastasis via upregulation of its target gene, 14/November/2017, 12.59 am
Probiotic-based therapy for metastatic prostate cancer: Lactobacillus Rhamnosus inhibits the expression of CDC42, CDC42EP3, RAC1 and ARPC5, and GAS6, suppresses the expression of stem cell molecules CD44 and EZH2, promotes epithelial phenotype, suppresses tumorigenesis, migration, invasion, stem cell regeneration and metastasis via upregulation of its target gene, 14/November/2017, 12.59 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from the Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Science Park, Texas 78957, USA shows that “MicroRNA-141 suppresses…

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Probiotic-based therapy for Hepatocellular carcinoma: Probiotic Lactobacillus Rhamnosus attenuates phosphoenolpyruvate carboxykinase (PEPCK1) sumoylation, stabilizes PEPCK1 levels, promotes gluconeogenesis, inhibits glycolysis and attenuates the progression of hepatocellular carcinoma via upregulation of its target gene, 14/December/2018, 12.36 pm
Probiotic-based therapy for Hepatocellular carcinoma: Probiotic Lactobacillus Rhamnosus attenuates phosphoenolpyruvate carboxykinase (PEPCK1) sumoylation, stabilizes PEPCK1 levels, promotes gluconeogenesis, inhibits glycolysis and attenuates the progression of hepatocellular carcinoma via upregulation of its target gene, 14/December/2018, 12.36 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from the State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Fujian Province, Xiamen…

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A sweet way to treat Metastatic cancers: Xylobiose, a disaccharide of xylose, increases the expression of tumor/metastatic suppressors PIAS3 and RhoB, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 14/November/2018, 12.24 am
A sweet way to treat Metastatic cancers: Xylobiose, a disaccharide of xylose, increases the expression of tumor/metastatic suppressors PIAS3 and RhoB, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 14/November/2018, 12.24 am 960 720 Dr Boomi's Genom-2-Discovery Center

From Significance of the study to Public health relevance:  Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more than half of them…

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Taming cancers with anti-tapeworm drugs: Niclosamide (brand name: Niclocide, Fenasal, Phenasal), an anti-tapeworm drug,  increases the expression of tumor suppressors genes, such as SMAD7, p12(DOC1/CDK2AP1), p53, TAp63, TAp73, INK4a/ARF, and others, and induces regression of p53-mutated human cancers and other cancers, via up-regulation of its target gene, 14/October/2018, 12.12 am
Taming cancers with anti-tapeworm drugs: Niclosamide (brand name: Niclocide, Fenasal, Phenasal), an anti-tapeworm drug,  increases the expression of tumor suppressors genes, such as SMAD7, p12(DOC1/CDK2AP1), p53, TAp63, TAp73, INK4a/ARF, and others, and induces regression of p53-mutated human cancers and other cancers, via up-regulation of its target gene, 14/October/2018, 12.12 am 960 720 Dr Boomi's Genom-2-Discovery Center

From Significance of the study to Public health relevance:  Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different tissue origin; (2) p53…

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Cancer therapy targeting cancer stem cells in chronic myelogenous leukemia (CML) and other metastatic cancers: Misoprostol, an FDA-approved EP4 agonist and abortion-promoting drug, increases the expression of tumor suppressor genes, such as HNF4α, CADM2, p53, and TA-p73/p63, targets CML leukemic stem cells, confers protection against CML and prolongs survival, via up-regulation of its target gene, 13/November/2018,11.20 pm
Cancer therapy targeting cancer stem cells in chronic myelogenous leukemia (CML) and other metastatic cancers: Misoprostol, an FDA-approved EP4 agonist and abortion-promoting drug, increases the expression of tumor suppressor genes, such as HNF4α, CADM2, p53, and TA-p73/p63, targets CML leukemic stem cells, confers protection against CML and prolongs survival, via up-regulation of its target gene, 13/November/2018,11.20 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from the Department of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA shows that “Prostaglandin E1 and…

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